The reference site for Terbutaline

Terbutaline (trade names “Bronclyn”,Brethine, Bricanyl, Brethaire, or Terbulin) is a β2 adrenergic receptor agonist, used as a “reliever” inhaler in the management of asthma symptoms.

WHAT IS Terbutaline?

Terbutaline is a bronchodilator (beta-2 receptor agonist) that works by opening breathing passages to make breathing easier.

Terbutaline is used to treat wheezing and shortness of breath from lung problems, such as asthma, chronic obstructive pulmonary disease, bronchitis and emphysema. Controlling these symptoms can decrease time lost from work or school, for example.

Terbutaline is sold under the brand names Brethine®, Bricanyl®, and Brethaire®.

 

Brand Name(s): Brethaire; Brethine; Bricanyl
CAS nº: 23031-25-6
(ter BYOO ta leen)

 

Product Info

The sections below will provide you with more specific information and guidelines related to terbutaline and its correct use. Please read them carefully.

FDA Information

Terbutaline was first approved by the Food and Drug Administration in 1974. A prescription is required for this medicine.

Note: it is not approved by the FDA for use as a pre-term labor drug, but it is sometimes used off-label for this purpose.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Terbutaline is used to treat wheezing and shortness of breath from lung problems (e.g. asthma, chronic obstructive pulmonary disease, bronchitis and emphysema). Controlling these symptoms can decrease time lost from work or school.

Terbutaline is a bronchodilator (beta-2 receptor agonist) that works by opening breathing passages to make breathing easier.

Other uses for this medicine

Although this use is not recommended by the manufacturer, terbutaline is also used in pregnant women to treat early labor.

However, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Terbutaline comes as tablets and as an aerosol inhalator to be taken orally.

The tablets are usually taken three times a day. The aerosol is used as needed to relieve symptoms or every 4-6 hours to prevent symptoms.

Take terbutaline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each tablet with a full glass of water.

It is important to take terbutaline regularly to get the most benefit.

Do not take terbutaline more often or in larger doses than is prescribed by your doctor. Taking more medication than is prescribed could be dangerous. Seek medical attention if you notice that you require more than your usual or more than the maximum amount of any asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.

Additionally, your doctor may want you to have lung function tests or other medical evaluations during treatment with terbutaline to monitor progress and side effects.

Before you use the terbutaline inhaler the first time, read the written instructions that come with it. Ask your doctor, pharmacist, or respiratory therapist to demonstrate the proper technique. Practice using the inhaler while in his or her presence.

To use the inhaler, follow these steps:

– Shake the inhaler well.
– Remove the protective cap.
– Exhale (breathe out) as completely as possible through your nose while keeping your mouth shut.

Open Mouth Technique: Open your mouth wide, and place the open end of the mouthpiece about 1-2 inches from your mouth.

Closed Mouth Technique: Place the open end of the mouthpiece well into your mouth, past your front teeth. Close your lips tightly around the mouthpiece.

– Take a slow, deep breath through the mouthpiece and, at the same time, press down on the container to spray the medication into your mouth. Be sure that the mist goes into your throat and is not blocked by your teeth or tongue. Adults giving the treatment to young children may hold the child’s nose closed to be sure that the medication goes into the child’s throat.
– Hold your breath for 5-10 seconds, remove the inhaler, and exhale slowly through your nose or mouth. If you take 2 puffs, wait 2 minutes and shake the inhaler well before taking the second puff.
– Replace the protective cap on the inhaler.
– If you have difficulty getting the medication into your lungs, a spacer (a special device that attaches to the inhaler) may help; ask your doctor, pharmacist, or respiratory therapist.

Terbutaline controls symptoms of asthma and other lung diseases but does not cure them. Continue to use terbutaline even if you feel well. Do not stop using terbutaline without talking to your doctor.

What special precautions should I follow?

BEFORE TAKING TERBUTALINE:

Tell your doctor if you have heart disease or high blood pressure, epilepsy or another seizure disorder, diabetes, an overactive thyroid (hyperthyroidism), liver disease, or kidney disease. You may not be able to take terbutaline or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Moreover, please inform your doctor if you are taking any of the following medication: a beta-blocker such as atenolol (Tenormin®), metoprolol (Lopressor®Toprol XL®), propranolol (Inderal®), acebutolol (Sectral®), bisoprolol (Zebeta®), carteolol (Cartrol®), carvedilol (Coreg®), labetalol (Normodyne®Trandate®), nadolol (Corgard®), or pindolol (Visken®); a tricyclic antidepressant such as amitriptyline (Elavil®), doxepin (Sinequan®), nortriptyline (Pamelor®), amoxapine (Asendin®), clomipramine (Anafranil®), desipramine (Norpramin®), imipramine (Tofranil®), or protriptyline (Vivactil®); a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan®), phenelzine (Nardil®), or tranylcypromine (Parnate®); another oral or inhaled bronchodilator; or caffeine, diet pills, or decongestants. You may not be able to take terbutaline, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above.

Drugs other than those listed here may also interact with terbutaline or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Avoid situations that may worsen your respiratory condition such as exercising in cold, dry air, smoking, breathing in dust, and exposure to allergens such as pet fur.

Terbutaline is in the FDA pregnancy category B. This means that terbutaline is not expected to be harmful to an unborn baby. Do not take terbutaline without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Nevertheless, terbutaline passes into breast milk and may affect a nursing baby. Do not take terbutaline without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed.

It is strongly advised not to take a double dose of this medication.

What side effects can this medication cause?

Stop taking terbutaline and seek emergency medical attention if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue, or face, or hives)
chest pain or irregular heartbeats

Other, less serious side effects may be more likely to occur. Continue to take terbutaline and talk to your doctor if you experience:

headache
dizziness or lightheadedness
insomnia
tremor or nervousness
sweating
nausea, vomiting, or diarrhea
dry mouth

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Please remember to throw away any medication that is outdated or no longer needed. If required, talk to your pharmacist about the proper disposal of your medication.

Note: try to avoid puncturing the container, and do not discard it in an incinerator or fire.

In case of an emergency/overdose

In the case of a suspected overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing,  then please call the local emergency services immediately on 911.

Symptoms of a terbutaline overdose may include:

angina or chest pain
irregular heartbeats or a fluttering heart
seizures
tremor
weakness
headache
nausea
vomiting

Product Images

PICTURES OF TERBUTALINE MEDICATION

Below you will find images and specific information on the principal types of terbutaline that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: TERBUTALINE
Strength(s): 5 MG
Imprint: 2622
Manufacturer: GLOBAL PHARMACEUTICALS

Name: TERBUTALINE
Strength(s): 1 MG/ML
Imprint: Terbutaline Sulfate Injection USP
Manufacturer: BEDFORD LABS.

Name: TERBUTALINE INJECTION
Strength(s): 1 MG/ML
Imprint: Terbutaline Sulfate Injection USP
Manufacturer: ABRAXIS BIOSCIENCE INC.

Name: TERBUTALINE
Strength(s): 60 ML
Imprint: TERBUTALINE
Manufacturer: UNITED LABS.

Name: BRICANYL® TURBUHALER
Strength(s): 500 MG
Imprint: Bricanyl® Turbuhaler
Manufacturer: ASTRA PHARMACEUTICALS

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